Publications

134        Ding, H., Groppa, S., & Muthuraman, M. (2022). Toward future adaptive deep brain stimulation for Parkinson’s disease: the novel biomarker – narrowband gamma oscillation. Neural Regen Res, 17(3), 557-558.               

133         Wang, Q., Akram, H., Muthuraman, M., Gonzalez-Escamilla, G., Sheth, S. A., Oxenford, S., Yeh, F. C., Groppa, S., Vanegas-Arroyave, N., Zrinzo, L., Li, N., Kühn, A., & Horn, A. (2021). Normative vs. patient-specific brain connectivity in deep brain stimulation. Neuroimage, 224(117307), 28.                  

132         Vedam-Mai, V., Deisseroth, K., Giordano, J., Lazaro-Munoz, G., Chiong, W., Suthana, N., Langevin, J. P., Gill, J., Goodman, W., Provenza, N. R., Halpern, C. H., Shivacharan, R. S., Cunningham, T. N., Sheth, S. A., Pouratian, N., Scangos, K. W., Mayberg, H. S., Horn, A., Johnson, K. A., Butson, C. R., Gilron, R., de Hemptinne         , C.       , Wilt, R., Yaroshinsky, M., Little, S., Starr, P., Worrell, G., Shirvalkar, P., Chang, E., Volkmann, J., Muthuraman, M., Groppa, S., Kühn, A. A., Li, L., Johnson, M., Otto, K. J., Raike, R., Goetz, S., Wu, C., Silburn, P., Cheeran, B., Pathak, Y. J., Malekmohammadi, M., Gunduz, A., Wong, J. K., Cernera, S., Hu, W., Wagle Shukla, A., Ramirez-Zamora, A., Deeb, W., Patterson, A., Foote, K. D., & Okun, M. S. (2021). Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Front Hum Neurosci, 15(644593).

131         Uphaus, T., Steffen, F., Muthuraman, M., Ripfel, N., Fleischer, V., Groppa, S., Ruck, T., Meuth, S. G., Pul, R., Kleinschnitz, C., Ellwardt, E., Loos, J., Engel, S., Zipp, F., & Bittner, S. (2021). NfL predicts relapse-free progression in a longitudinal multiple sclerosis cohort study. EBioMedicine, 72(103590), 24.                     

130         Seitz, C. B., Steffen, F., Muthuraman, M., Uphaus, T., Krämer, J., Meuth, S. G., Albrecht, P., Groppa, S., Zipp, F., Bittner, S., & Fleischer, V. (2021). Serum neurofilament levels reflect outer retinal layer changes in multiple sclerosis. Ther Adv Neurol Disord, 14(17562864211003478).                       

129         Ring, P., Keil, J., Muthuraman, M., Wolff, S., Bergmann, T. O., Probst, C., Neyse, L., Schmidt, U., van Eimeren, T., & Kaernbach, C. (2021). Oscillatory brain activity associated with skin conductance responses in the context of risk. J Neurophysiol, 126(3), 924-933.              

128         Radetz, A., Mladenova, K., Ciolac, D., Gonzalez-Escamilla, G., Fleischer, V., Ellwardt, E., Krämer, J., Bittner, S., Meuth, S. G., Muthuraman, M., & Groppa, S. (2021). Linking Microstructural Integrity and Motor Cortex Excitability in Multiple Sclerosis. Front Immunol, 12(748357).                 

127         Pavlov, Y. G., Adamian, N., Appelhoff, S., Arvaneh, M., Benwell, C. S. Y., Beste, C., Bland, A. R., Bradford, D. E., Bublatzky, F., Busch, N. A., Clayson, P. E., Cruse, D., Czeszumski, A., Dreber, A., Dumas, G., Ehinger, B., Ganis, G., He, X., Hinojosa, J. A., Huber-Huber, C., Inzlicht, M., Jack, B. N., Johannesson, M., Jone      s, R      ., Kalenkovich, E., Kaltwasser, L., Karimi-Rouzbahani, H., Keil, A., König, P., Kouara, L., Kulke, L., Ladouceur, C. D., Langer, N., Liesefeld, H. R., Luque, D., MacNamara, A., Mudrik, L., Muthuraman, M., Neal, L. B., Nilsonne, G., Niso, G., Ocklenburg, S., Oostenveld, R., Pernet, C. R., Pourtois, G., Ruzzoli, M., Sass, S. M., Schaefer, A., Senderecka, M., Snyder, J. S., Tamnes, C. K., Tognoli, E., van Vugt, M. K., Verona, E., Vloeberghs, R., Welke, D., Wessel, J. R., Zakharov, I., & Mushtaq, F. (2021). #EEGManyLabs: Investigating the replicability of influential EEG experiments. Cortex, 144, 213-229.

126         Muthuraman, M., Palotai, M., Jávor-Duray, B., Kelemen, A., Koirala, N., Halász, L., Erőss, L., Fekete, G., Bognár, L., Deuschl, G., & Tamás, G. (2021). Frequency-specific network activity predicts bradykinesia severity in Parkinson’s disease. Neuroimage Clin, 32(102857), 102857.               

125      Michels, L., Koirala, N., Groppa, S., Luechinger, R., Gantenbein, A. R., Sandor, P. S., Kollias, S., Riederer, F., & Muthuraman, M. (2021). Structural brain network characteristics in patients with episodic and chronic migraine. J Headache Pain, 22(1), 021-01216.                

124      McMackin, R., Dukic, S., Costello, E., Pinto-Grau, M., McManus, L., Broderick, M., Chipika, R., Iyer, P. M., Heverin, M., Bede, P., Muthuraman, M., Pender, N., Hardiman, O., & Nasseroleslami, B. (2021). Cognitive network hyperactivation and motor cortex decline correlate with ALS prognosis. Neurobiol Aging, 104, 57-70.                   

123      Litvak, V., Florin, E., Tamás, G., Groppa, S., & Muthuraman, M. (2021). EEG and MEG primers for tracking DBS network effects. Neuroimage, 224(117447), 12.                   

122      Leahu, P., Bange, M., Ciolac, D., Scheiter, S., Matei, A., Gonzalez-Escamilla, G., Chirumamilla, V. C., Groppa, S. A., Muthuraman, M., & Groppa, S. (2021). Increased migraine-free intervals with multifocal repetitive transcranial magnetic stimulation. Brain Stimul, 14(6), 1544-1552.                       

121      Kreis, S. L., Luhmann, H. J., Ciolac, D., Groppa, S., & Muthuraman, M. (2021). Translational Model of Cortical Premotor-Motor Networks. Cereb Cortex, 23(10).            

120      Khastkhodaei, Z., Muthuraman, M., Yang, J. W., Groppa, S., & Luhmann, H. J. (2021). Functional and directed connectivity of the cortico-limbic network in mice in vivo. Brain Struct Funct, 226(3), 685-700.                       

119      Hallett, M., DelRosso, L. M., Elble, R., Ferri, R., Horak, F. B., Lehericy, S., Mancini, M., Matsuhashi, M., Matsumoto, R., Muthuraman, M., Raethjen, J., & Shibasaki, H. (2021). Evaluation of movement and brain activity. Clin Neurophysiol, 132(10), 2608-2638.                      

118      Gonzalez-Escamilla, G., Miederer, I., Grothe, M. J., Schreckenberger, M., Muthuraman, M., & Groppa, S. (2021). Metabolic and amyloid PET network reorganization in Alzheimer’s disease: differential patterns and partial volume effects. Brain Imaging Behav, 15(1), 190-204.            

117      Fleischer, V., Gonzalez-Escamilla, G., Ciolac, D., Albrecht, P., Küry, P., Gruchot, J., Dietrich, M., Hecker, C., Müntefering, T., Bock, S., Oshaghi, M., Radetz, A., Cerina, M., Krämer, J., Wachsmuth, L., Faber, C., Lassmann, H., Ruck, T., Meuth, S. G., Muthuraman, M., & Groppa, S. (2021). Translational value of choroid plexus ima      ging for tracking neuroinflammation in mice and humans. Proc Natl Acad Sci U S A, 118(36), 2025000118.

116      Dukic, S., McMackin, R., Costello, E., Metzger, M., Buxo, T., Fasano, A., Chipika, R., Pinto-Grau, M., Schuster, C., Hammond, M., Heverin, M., Coffey, A., Broderick, M., Iyer, P. M., Mohr, K., Gavin, B., McLaughlin, R., Pender, N., Bede, P., Muthuraman, M., van den Berg, L., Hardiman, O., & Nasseroleslami, B. (2021). Resting-s  tate     EEG reveals four subphenotypes of amyotrophic lateral sclerosis. Brain, 17(10).

115      Coffey, A., Bista, S., Fasano, A., Buxo, T., Mitchell, M., Giglia, E. R., Dukic, S., Fenech, M., Barry, M., Wade, A., Heverin, M., Muthuraman, M., Carson, R. G., Lowery, M., Hardiman, O., & Nasseroleslami, B. (2021). Altered supraspinal motor networks in survivors of poliomyelitis: A cortico-muscular coherence study. Clin Neur ophy    siol, 132(1), 106-113.

114      Ciolac, D., Gonzalez-Escamilla, G., Radetz, A., Fleischer, V., Person, M., Johnen, A., Landmeyer, N. C., Krämer, J., Muthuraman, M., Meuth, S. G., & Groppa, S. (2021). Sex-specific signatures of intrinsic hippocampal networks and regional integrity underlying cognitive status in multiple sclerosis. Brain Commun, 3(3).                      

113      Bange, M., Groppa, S., & Muthuraman, M. (2021). Nonlinear irregularities in Parkinson’s disease tremor and essential tremor. Clin Neurophysiol. , 132(9), 2255-2256.              

112      Bange, M., Gonzalez-Escamilla, G., Marquardt, T., Radetz, A., Dresel, C., Herz, D., Schöllhorn, W. I., Groppa, S., & Muthuraman, M. (2021). Deficient Interhemispheric Connectivity Underlies Movement Irregularities in Parkinson’s Disease. J Parkinsons Dis, 23(10), JPD-212840.                   

111      Bahr, K., Geisler, V., Huppertz, T., Groppa, S., Matthias, C., Gouveris, H., & Muthuraman, M. (2021). Intensity of Respiratory Cortical Arousals Is a Distinct Pathophysiologic Feature and Is Associated with Disease Severity in Obstructive Sleep Apnea Patients. Brain Sci, 11(3).                

110      Wiest, C., Tinkhauser, G., Pogosyan, A., Bange, M., Muthuraman, M., Groppa, S., Baig, F., Mostofi, A., Pereira, E. A., Tan, H., Brown, P., & Torrecillos, F. (2020). Local field potential activity dynamics in response to deep brain stimulation of the subthalamic nucleus in Parkinson’s disease. Neurobiol Dis, 143(105019), 16.                   

109      Tinkhauser, G., Torrecillos, F., Pogosyan, A., Mostofi, A., Bange, M., Fischer, P., Tan, H., Hasegawa, H., Glaser, M., Muthuraman, M., Groppa, S., Ashkan, K., Pereira, E. A., & Brown, P. (2020). The Cumulative Effect of Transient Synchrony States on Motor Performance in Parkinson’s Disease. J Neurosci, 40(7), 1571-1580.            

108      Radetz, A., Koirala, N., Krämer, J., Johnen, A., Fleischer, V., Gonzalez-Escamilla, G., Cerina, M., Muthuraman, M., Meuth, S. G., & Groppa, S. (2020). Gray matter integrity predicts white matter network reorganization in multiple sclerosis. Hum Brain Mapp, 41(4), 917-927.                

107      Muthuraman, M., Fleischer, V., Kroth, J., Ciolac, D., Radetz, A., Koirala, N., Gonzalez-Escamilla, G., Wiendl, H., Meuth, S. G., Zipp, F., & Groppa, S. (2020). Covarying patterns of white matter lesions and cortical atrophy predict progression in early MS. Neurol Neuroimmunol Neuroinflamm, 7(3), 4.                      

106      Muthuraman, M., Bange, M., Koirala, N., Ciolac, D., Pintea, B., Glaser, M., Tinkhauser, G., Brown, P., Deuschl, G., & Groppa, S. (2020). Cross-frequency coupling between gamma oscillations and deep brain stimulation frequency in Parkinson’s disease. Brain, 143(11), 3393-3407.                 

105      Muthuraman, M., Bange, M., & Groppa, S. (2020). Advanced technologies for detecting tremor in Parkinson’s disease. Clin Neurophysiol. , 131(1).           

104      McMackin, R., Dukic, S., Costello, E., Pinto-Grau, M., Fasano, A., Buxo, T., Heverin, M., Reilly, R., Muthuraman, M., Pender, N., Hardiman, O., & Nasseroleslami, B. (2020). Localization of Brain Networks Engaged by the Sustained Attention to Response Task Provides Quantitative Markers of Executive Impairment in Amyotrophic Lat eral      Sclerosis. Cereb Cortex, 30(9), 4834-4846.

103      Lurie, D. J., Kessler, D., Bassett, D. S., Betzel, R. F., Breakspear, M., Kheilholz, S., Kucyi, A., Liégeois, R., Lindquist, M. A., McIntosh, A. R., Poldrack, R. A., Shine, J. M., Thompson, W. H., Bielczyk, N. Z., Douw, L., Kraft, D., Miller, R. L., Muthuraman, M., Pasquini, L., Razi, A., Vidaurre, D., Xie, H., & Calhoun, V. D          . (2       020). Questions and controversies in the study of time-varying functional connectivity in resting fMRI. [Review]. Netw Neurosci, 4(1), 30-69.

102      Koirala, N., Serrano, L., Paschen, S., Falk, D., Anwar, A. R., Kuravi, P., Deuschl, G., Groppa, S., & Muthuraman, M. (2020). Mapping of subthalamic nucleus using microelectrode recordings during deep brain stimulation. Sci Rep, 10(1), 020-74196.           

101      Hossen, A., Deuschl, G., Groppa, S., Heute, U., & Muthuraman, M. (2020). Discrimination of physiological tremor from pathological tremor using accelerometer and surface EMG signals. Technol Health Care, 28(5), 461-476.                    

100      Gouveris, H., Bahr, K., Schmitt, E., Abriani, A., Boekstegers, T., Fassnacht, S., Huppertz, T., Groppa, S., & Muthuraman, M. (2020). Corticoperipheral neuromuscular disconnection in obstructive sleep apnoea. Brain Commun, 2(1).                    

99        Gonzalez-Escamilla, G., Muthuraman, M., Ciolac, D., Coenen, V. A., Schnitzler, A., & Groppa, S. (2020). Neuroimaging and electrophysiology meet invasive neurostimulation for causal interrogations and modulations of brain states. Neuroimage, 220(117144), 4.                     

98        Gonzalez-Escamilla, G., Ciolac, D., De Santis, S., Radetz, A., Fleischer, V., Droby, A., Roebroeck, A., Meuth, S. G., Muthuraman, M., & Groppa, S. (2020). Gray matter network reorganization in multiple sclerosis from 7-Tesla and 3-Tesla MRI data. Ann Clin Transl Neurol, 7(4), 543-553.            

97        Fleischer, V., Muthuraman, M., Anwar, A. R., Gonzalez-Escamilla, G., Radetz, A., Gracien, R. M., Bittner, S., Luessi, F., Meuth, S. G., Zipp, F., & Groppa, S. (2020). Continuous reorganization of cortical information flow in multiple sclerosis: A longitudinal fMRI effective connectivity study. Sci Rep, 10(1), 020-57895.                 

96        Engel, S., Graetz, C., Salmen, A., Muthuraman, M., Toenges, G., Ambrosius, B., Bayas, A., Berthele, A., Heesen, C., Klotz, L., Kümpfel, T., Linker, R. A., Meuth, S. G., Paul, F., Stangel, M., Tackenberg, B., Then Bergh, F., Tumani, H., Weber, F., Wildemann, B., Zettl, U. K., Antony, G., Bittner, S., Groppa, S., Hemmer, B., Wie        ndl,      H., Gold, R., Zipp, F., Lill, C. M., & Luessi, F. (2020). Is APOE ε4 associated with cognitive performance in early MS? Neurol Neuroimmunol Neuroinflamm, 7(4).

95        Cerina, M., Muthuraman, M., Gallus, M., Koirala, N., Dik, A., Wachsmuth, L., Hundehege, P., Schiffler, P., Tenberge, J. G., Fleischer, V., Gonzalez-Escamilla, G., Narayanan, V., Krämer, J., Faber, C., Budde, T., Groppa, S., & Meuth, S. G. (2020). Myelination- and immune-mediated MR-based brain network correlates. J Neuroinflam         mati     on, 17(1), 020-01827.

94        Bittner, S., Steffen, F., Uphaus, T., Muthuraman, M., Fleischer, V., Salmen, A., Luessi, F., Berthele, A., Klotz, L., Meuth, S. G., Bayas, A., Paul, F., Hartung, H. P., Linker, R., Heesen, C., Stangel, M., Wildemann, B., Then Bergh, F., Tackenberg, B., Kuempfel, T., Weber, F., Zettl, U. K., Ziemann, U., Tumani, H., Groppa, S.,     Müh    lau, M., Lukas, C., Hemmer, B., Wiendl, H., Gold, R., & Zipp, F. (2020). Clinical implications of serum neurofilament in newly diagnosed MS patients: A longitudinal multicentre cohort study. EBioMedicine, 56(102807), 24.

93        Uphaus, T., Bittner, S., Gröschel, S., Steffen, F., Muthuraman, M., Wasser, K., Weber-Krüger, M., Zipp, F., Wachter, R., & Gröschel, K. (2019). NfL (Neurofilament Light Chain) Levels as a Predictive Marker for Long-Term Outcome After Ischemic Stroke. Stroke, 50(11), 3077-3084.                   

92        Siller, N., Kuhle, J., Muthuraman, M., Barro, C., Uphaus, T., Groppa, S., Kappos, L., Zipp, F., & Bittner, S. (2019). Serum neurofilament light chain is a biomarker of acute and chronic neuronal damage in early multiple sclerosis. Mult Scler, 25(5), 678-686.                    

91        Pflug, A., Gompf, F., Muthuraman, M., Groppa, S., & Kell, C. A. (2019). Differential contributions of the two human cerebral hemispheres to action timing. Elife, 7(8), 48404.                   

90        Muthuraman, M., Moliadze, V., Boecher, L., Siemann, J., Freitag, C. M., Groppa, S., & Siniatchkin, M. (2019). Multimodal alterations of directed connectivity profiles in patients with attention-deficit/hyperactivity disorders. Sci Rep, 9(1), 019-56398.                     

89        Michels, L., Villanueva, J., O’Gorman, R., Muthuraman, M., Koirala, N., Büchler, R., Gantenbein, A. R., Sandor, P. S., Luechinger, R., Kollias, S., & Riederer, F. (2019). Interictal Hyperperfusion in the Higher Visual Cortex in Patients With Episodic Migraine. Headache, 59(10), 1808-1820.                       

88        McMackin, R., Muthuraman, M., Groppa, S., Babiloni, C., Taylor, J. P., Kiernan, M. C., Nasseroleslami, B., & Hardiman, O. (2019). Measuring network disruption in neurodegenerative diseases: New approaches using signal analysis. J Neurol Neurosurg Psychiatry, 90(9), 1011-1020.             

87        McMackin, R., Dukic, S., Broderick, M., Iyer, P. M., Pinto-Grau, M., Mohr, K., Chipika, R., Coffey, A., Buxo, T., Schuster, C., Gavin, B., Heverin, M., Bede, P., Pender, N., Lalor, E. C., Muthuraman, M., Hardiman, O., & Nasseroleslami, B. (2019). Dysfunction of attention switching networks in amyotrophic lateral sclerosis. Neu     roim    age Clin, 22(101707), 2.

86        Kroth, J., Ciolac, D., Fleischer, V., Koirala, N., Krämer, J., Muthuraman, M., Luessi, F., Bittner, S., Gonzalez-Escamilla, G., Zipp, F., Meuth, S. G., & Groppa, S. (2019). Increased cerebrospinal fluid albumin and immunoglobulin A fractions forecast cortical atrophy and longitudinal functional deterioration in relapsing-remit         ting      multiple sclerosis. Mult Scler, 25(3), 338-343.

85        Koirala, N., Anwar, A. R., Ciolac, D., Glaser, M., Pintea, B., Deuschl, G., Muthuraman, M., & Groppa, S. (2019). Alterations in White Matter Network and Microstructural Integrity Differentiate Parkinson’s Disease Patients and Healthy Subjects. Front Aging Neurosci, 11(191).                      

84        Gonzalez-Escamilla, G., Muthuraman, M., Reich, M. M., Koirala, N., Riedel, C., Glaser, M., Lange, F., Deuschl, G., Volkmann, J., & Groppa, S. (2019). Cortical network fingerprints predict deep brain stimulation outcome in dystonia. Mov Disord, 34(10), 1537-1546.                  

83        Fleischer, V., Radetz, A., Ciolac, D., Muthuraman, M., Gonzalez-Escamilla, G., Zipp, F., & Groppa, S. (2019). Graph Theoretical Framework of Brain Networks in Multiple Sclerosis: A Review of Concepts. Neuroscience, 403, 35-53.               

82        Fleischer, V., Koirala, N., Droby, A., Gracien, R. M., Deichmann, R., Ziemann, U., Meuth, S. G., Muthuraman, M., Zipp, F., & Groppa, S. (2019). Longitudinal cortical network reorganization in early relapsing-remitting multiple sclerosis. Ther Adv Neurol Disord, 12(1756286419838673).            

81        Engel, S., Friedrich, M., Muthuraman, M., Steffen, F., Poplawski, A., Groppa, S., Bittner, S., Zipp, F., & Luessi, F. (2019). Intrathecal B-cell accumulation and axonal damage distinguish MRI-based benign from aggressive onset in MS. Neurol Neuroimmunol Neuroinflamm, 6(5).                

80        Dukic, S., McMackin, R., Buxo, T., Fasano, A., Chipika, R., Pinto-Grau, M., Costello, E., Schuster, C., Hammond, M., Heverin, M., Coffey, A., Broderick, M., Iyer, P. M., Mohr, K., Gavin, B., Pender, N., Bede, P., Muthuraman, M., Lalor, E. C., Hardiman, O., & Nasseroleslami, B. (2019). Patterned functional network disruption in  amy     otrophic lateral sclerosis. Hum Brain Mapp, 40(16), 4827-4842.

79        Ciolac, D., Luessi, F., Gonzalez-Escamilla, G., Koirala, N., Riedel, C., Fleischer, V., Bittner, S., Krämer, J., Meuth, S. G., Muthuraman, M., & Groppa, S. (2019). Selective Brain Network and Cellular Responses Upon Dimethyl Fumarate Immunomodulation in Multiple Sclerosis. Front Immunol, 10(1779).               

78        Chirumamilla, V. C., Gonzalez-Escamilla, G., Koirala, N., Bonertz, T., von Grotthus, S., Muthuraman, M., & Groppa, S. (2019). Cortical Excitability Dynamics During Fear Processing. Front Neurosci, 13(568).                 

77        Chirumamilla, V. C., Dresel, C., Koirala, N., Gonzalez-Escamilla, G., Deuschl, G., Zeuner, K. E., Muthuraman, M., & Groppa, S. (2019). Structural brain network fingerprints of focal dystonia. Ther Adv Neurol Disord, 12(1756286419880664).                      

76        Chiosa, V., Ciolac, D., Groppa, S., Koirala, N., Pintea, B., Vataman, A., Winter, Y., Gonzalez-Escamilla, G., & Muthuraman, M. (2019). Large-scale network architecture and associated structural cortico-subcortical abnormalities in patients with sleep/awake-related seizures. Sleep, 42(4).                       

75        Vergotte, G., Perrey, S., Muthuraman, M., Janaqi, S., & Torre, K. (2018). Concurrent Changes of Brain Functional Connectivity and Motor Variability When Adapting to Task Constraints. Front Physiol, 9(909).                    

74        Tamás, G., Chirumamilla, V. C., Anwar, A. R., Raethjen, J., Deuschl, G., Groppa, S., & Muthuraman, M. (2018). Primary Sensorimotor Cortex Drives the Common Cortical Network for Gamma Synchronization in Voluntary Hand Movements. Front Hum Neurosci, 12(130).                   

73        Muthuraman, M., Schnitzler, A., & Groppa, S. (2018). [Pathophysiology of tremor]. [Review]. Nervenarzt, 89(4), 408-415.                   

72        Muthuraman, M., Raethjen, J., Koirala, N., Anwar, A. R., Mideksa, K. G., Elble, R., Groppa, S., & Deuschl, G. (2018). Cerebello-cortical network fingerprints differ between essential, Parkinson’s and mimicked tremors. Brain, 141(6), 1770-1781.                   

71        Muthuraman, M., Koirala, N., Ciolac, D., Pintea, B., Glaser, M., Groppa, S., & Tamás, G. (2018). Deep Brain Stimulation and L-DOPA Therapy: Concepts of Action and Clinical Applications in Parkinson’s Disease. [Review]. Front Neurol, 9(711).                   

70        Koirala, N., Fleischer, V., Glaser, M., Zeuner, K. E., Deuschl, G., Volkmann, J., Muthuraman, M., & Groppa, S. (2018). Frontal Lobe Connectivity and Network Community Characteristics are Associated with the Outcome of Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson’s Disease. Brain Topogr, 31(2), 311-321.              

69        Gonzalez-Escamilla, G., Muthuraman, M., Chirumamilla, V. C., Vogt, J., & Groppa, S. (2018). Brain Networks Reorganization During Maturation and Healthy Aging-Emphases for Resilience. [Review]. Front Psychiatry, 9(601).                    

68        Gonzalez-Escamilla, G., Chirumamilla, V. C., Meyer, B., Bonertz, T., von Grotthus, S., Vogt, J., Stroh, A., Horstmann, J. P., Tüscher, O., Kalisch, R., Muthuraman, M., & Groppa, S. (2018). Excitability regulation in the dorsomedial prefrontal cortex during sustained instructed fear responses: a TMS-EEG study. Sci Rep, 8(1), 01     Aug-32 781

67        Allert, N., Cheeran, B., Deuschl, G., Barbe, M. T., Csoti, I., Ebke, M., Glaser, M., Kang, J. S., Kelm, S., Krack, P., Kroth, J., Jobst, U., Leisse, M., Oliviero, A., Nolte, P. N., Quick-Weller, J., Strothjohann, M., Tamás, G., Werner, M., Muthuraman, M., Volkmann, J., Fasano, A., & Groppa, S. (2018). Postoperative rehabilitat        ion       after deep brain stimulation surgery for movement disorders. [Review]. Clin Neurophysiol, 129(3), 592-601.

66        Vergotte, G., Torre, K., Chirumamilla, V. C., Anwar, A. R., Groppa, S., Perrey, S., & Muthuraman, M. (2017). Dynamics of the human brain network revealed by time-frequency effective connectivity in fNIRS. Biomed Opt Express, 8(11), 5326-5341.                 

65        Schlenstedt, C., Shalash, A., Muthuraman, M., Falk, D., Witt, K., & Deuschl, G. (2017). Effect of high-frequency subthalamic neurostimulation on gait and freezing of gait in Parkinson’s disease: a systematic review and meta-analysis. Eur J Neurol, 24(1), 18-26.               

64        Muthuraman, M., Deuschl, G., Koirala, N., Riedel, C., Volkmann, J., & Groppa, S. (2017). Effects of DBS in parkinsonian patients depend on the structural integrity of frontal cortex. Sci Rep, 7(43571).            

63        Michels, L., Muthuraman, M., Anwar, A. R., Kollias, S., Leh, S. E., Riese, F., Unschuld, P. G., Siniatchkin, M., Gietl, A. F., & Hock, C. (2017). Changes of Functional and Directed Resting-State Connectivity Are Associated with Neuronal Oscillations, ApoE Genotype and Amyloid Deposition in Mild Cognitive Impairment. Front Agin      g Ne     urosci, 9(304).

62        Japaridze, N., Muthuraman, M., Dierck, C., von Spiczak, S., Stephani, U., & Siniatchkin, M. (2017). In response: Neuronal networks in epileptic encephalopathies with CSWS. Epilepsia. , 58(7), 1297-1298.                       

61        Fleischer, V., Gröger, A., Koirala, N., Droby, A., Muthuraman, M., Kolber, P., Reuter, E., Meuth, S. G., Zipp, F., & Groppa, S. (2017). Increased structural white and grey matter network connectivity compensates for functional decline in early multiple sclerosis. Mult Scler, 23(3), 432-441.                       

60        Chirumamilla, V., Gonzalez-Escamilla, G., Kumar, S., Longfei, X., Groppa, S., & Muthuraman, M. (2017). Establishing and validating a new source analysis method using phase. Annu Int Conf IEEE Eng Med Biol Soc, 10, 8037433.             

59        Chiosa, V., Groppa, S. A., Ciolac, D., Koirala, N., Mişina, L., Winter, Y., Moldovanu, M., Muthuraman, M., & Groppa, S. (2017). Breakdown of Thalamo-Cortical Connectivity Precedes Spike Generation in Focal Epilepsies. Brain Connect, 7(5), 309-320.                  

58        Schlenstedt, C., Muthuraman, M., Witt, K., Weisser, B., Fasano, A., & Deuschl, G. (2016). Postural control and freezing of gait in Parkinson’s disease. Parkinsonism Relat Disord, 24, 107-112.                

57        Muthuraman, M., Hartwigsen, G., & Groppa, S. (2016). (Non-) invasive mapping of cortical language areas. Clin Neurophysiol., 127(3), 1762-1763.              

56        Muthuraman, M., Groppa, S., & Deuschl, G. (2016). Cerebello-cortical networks in orthostatic tremor. [Comment]. Brain, 139(Pt 8), 2104-2106.              

55        Muthuraman, M., Fleischer, V., Kolber, P., Luessi, F., Zipp, F., & Groppa, S. (2016). Structural Brain Network Characteristics Can Differentiate CIS from Early RRMS. Front Neurosci, 10(14).                      

54        Muthuraman, M., Chirumamilla, C. V., & Groppa, S. (2016). Establishing standards for neuronavigated TMS in research and clinical studies. Clin Neurophysiol. , 127(8), 2890-2891.                    

53        Mideksa, K. G., Singh, A., Hoogenboom, N., Hellriegel, H., Krause, H., Schnitzler, A., Deuschl, G., Raethjen, J., Schmidt, G., & Muthuraman, M. (2016). Comparison of imaging modalities and source-localization algorithms in locating the induced activity during deep brain stimulation of the STN. [Comparative Study]. Annu Int Con f IE       EE Eng Med Biol Soc, 7590651.

52        Koirala, N., Fleischer, V., Granert, O., Deuschl, G., Muthuraman, M., & Groppa, S. (2016). Network effects and pathways in Deep brain stimulation in Parkinson’s disease. [Randomized Controlled Trial]. Annu Int Conf IEEE Eng Med Biol Soc, 10, 7591980.              

51        Japaridze, N., Muthuraman, M., Dierck, C., von Spiczak, S., Boor, R., Mideksa, K. G., Anwar, R. A., Deuschl, G., Stephani, U., & Siniatchkin, M. (2016). Neuronal networks in epileptic encephalopathies with CSWS. Epilepsia, 57(8), 1245-1255.                

50        Droby, A., Yuen, K. S., Muthuraman, M., Reitz, S. C., Fleischer, V., Klein, J., Gracien, R. M., Ziemann, U., Deichmann, R., Zipp, F., & Groppa, S. (2016). Changes in brain functional connectivity patterns are driven by an individual lesion in MS: a resting-state fMRI study. [Research Support, Non-U S Gov’t]. Brain Imaging Beha   v, 1      0(4), 1117-1126.

49        Chirumamilla, V. C., Fleischer, V., Droby, A., Anjum, T., Muthuraman, M., Zipp, F., & Groppa, S. (2016). Functional connectivity analysis using whole brain and regional network metrics in MS patients. Annu Int Conf IEEE Eng Med Biol Soc, 10, 7591613.               

48        Caldero-Bardaji, P., Longfei, X., Jaschke, S., Reermann, J., Mideska, K. G., Schmidt, G., Deuschl, G., & Muthuraman, M. (2016). Detection of steering direction using EEG recordings based on sample entropy and time-frequency analysis. Annu Int Conf IEEE Eng Med Biol Soc, 7590830.                       

47        Anwar, A. R., Muthalib, M., Perrey, S., Galka, A., Granert, O., Wolff, S., Heute, U., Deuschl, G., Raethjen, J., & Muthuraman, M. (2016). Effective Connectivity of Cortical Sensorimotor Networks During Finger Movement Tasks: A Simultaneous fNIRS, fMRI, EEG Study. Brain Topogr, 29(5), 645-660.                      

46        Anwar, A. R., Hashmy, M. Y., Imran, B., Riaz, M. H., Mehdi, S. M., Muthalib, M., Perrey, S., Deuschl, G., Groppa, S., & Muthuraman, M. (2016). Complex network analysis of resting-state fMRI of the brain. Annu Int Conf IEEE Eng Med Biol Soc, 10, 7591506.                      

45        Alexandru, H., Muthuraman, M., Chirumamilla, V. C., Koirala, N., Paktas, B., Deuschl, G., Zeuner, K. E., & Groppa, S. (2016). Grey Matter Microstructural Integrity Alterations in Blepharospasm Are Partially Reversed by Botulinum Neurotoxin Therapy. PLoS One, 11(12).               

44        Raethjen, J., & Muthuraman, M. (2015). Cause or compensation? Complex changes in cerebello-thalamo-cortical networks in pathological action tremor. [Comment]. Brain, 138(Pt 10), 2808-2810.              

43        Muthuraman, M., Moliadze, V., Mideksa, K. G., Anwar, A. R., Stephani, U., Deuschl, G., Freitag, C. M., & Siniatchkin, M. (2015). EEG-MEG Integration Enhances the Characterization of Functional and Effective Connectivity in the Resting State Network. PLoS One, 10(10).               

42        Muthuraman, M., Dohring, J., Nahrwold, M., Mideksa, K. G., Chaitanya, C. V., Margraf, N., Raethjen, J., Deuschl, G., & Bartsch, T. (2015). Voxel seed coherent source analysis on transient global amnesia patients. Annu Int Conf IEEE Eng Med Biol Soc, 7318443.                  

41        Muthuraman, M., Deuschl, G., Anwar, A. R., Mideksa, K. G., von Helmolt, F., & Schneider, S. A. (2015). Essential and aging-related tremor: Differences of central control. Mov Disord, 30(12), 1673-1680.                  

40        Muthuraman, M., Anjum, T., Droby, A., Fleischer, V., Reitz, S., Mideksa, K., Schmidt, G., Zipp, F., & Groppa, S. (2015). Testing different ICA algorithms and connectivity analyses on MS patients. Annu Int Conf IEEE Eng Med Biol Soc, 7(10), 7319349.                 

39        Mideksa, K. G., Hoogenboom, N., Hellriegel, H., Krause, H., Schnitzler, A., Deuschl, G., Raethjen, J., Heute, U., & Muthuraman, M. (2015). Comparison of EEG and MEG in source localization of induced human gamma-band oscillations during visual stimulus. [Comparative Study]. Annu Int Conf IEEE Eng Med Biol Soc, 22(10), 7320278.                

38        Koirala, N., Muthuraman, M., Anjum, T., Chaitanya, C. V., Helmolt, V. F., Mideksa, K. G., Lange, K., Schmidt, G., Schneider, S., & Deuschl, G. (2015). Differentiating tremor patients using spiral analyses. [Research Support, Non-U S Gov’t]. Annu Int Conf IEEE Eng Med Biol Soc, 30(10), 7319815.                    

37        Japaridze, N., Muthuraman, M., Reinicke, C., Moeller, F., Anwar, A. R., Mideksa, K. G., Pressler, R., Deuschl, G., Stephani, U., & Siniatchkin, M. (2015). Neuronal Networks during Burst Suppression as Revealed by Source Analysis. PLoS One, 10(4).                    

36        Chaitanya, C. V., Koirala, N., Mideksa, K. G., Anwar, A. R., Schmidt, G., Deuschl, G., Groppa, S., & Muthuraman, M. (2015). Testing the effects of pre-processing on voxel based morphometry analysis. Annu Int Conf IEEE Eng Med Biol Soc, 5(10), 7319346.            

35        Muthuraman, M., Hellriegel, H., Hoogenboom, N., Anwar, A. R., Mideksa, K. G., Krause, H., Schnitzler, A., Raethjen, J., & Deuschl, G. (2014). Coherent source and connectivity analysis on simultaneously measured EEG and MEG data during isometric contraction. Annu Int Conf IEEE Eng Med Biol Soc, 8(10), 6945084.                      

34        Muthuraman, M., Hellriegel, H., Hoogenboom, N., Anwar, A. R., Mideksa, K. G., Krause, H., Schnitzler, A., Deuschl, G., & Raethjen, J. (2014). Beamformer source analysis and connectivity on concurrent EEG and MEG data during voluntary movements. PLoS One, 9(3).           

33        Mideksa, K. G., Santillan-Guzman, A., Japaridze, N., Galka, A., Stephani, U., Deuschl, G., Heute, U., & Muthuraman, M. (2014). Validating the effect of muscle artifact suppression in localizing focal epilepsy. Annu Int Conf IEEE Eng Med Biol Soc, 4(10), 6944461.                  

32        Mideksa, K. G., Hoogenboom, N., Hellriegel, H., Krause, H., Schnitzler, A., Deuschl, G., Raethjen, J., Heute, U., & Muthuraman, M. (2014). Impact of head modeling and sensor types in localizing human gamma-band oscillations. Annu Int Conf IEEE Eng Med Biol Soc, 20(10), 6944059.                       

31        Anwar, A. R., Muthalib, M., Perrey, S., Wolff, S., Deuschl, G., Heute, U., & Muthuraman, M. (2014). Differences in hemispherical thalamo-cortical causality analysis during resting-state fMRI. Annu Int Conf IEEE Eng Med Biol Soc, 6943759.                   

30        Anwar, A. R., Mideska, K. G., Hellriegel, H., Hoogenboom, N., Krause, H., Schnitzler, A., Deuschl, G., Raethjen, J., Heute, U., & Muthuraman, M. (2014). Multi-modal causality analysis of eyes-open and eyes-closed data from simultaneously recorded EEG and MEG. Annu Int Conf IEEE Eng Med Biol Soc, 8(10), 6944211.                      

29        Santillán-Guzmán, A., Heute, U., Muthuraman, M., Stephani, U., & Galka, A. (2013). DBS artifact suppression using a time-frequency domain filter. Annu Int Conf IEEE Eng Med Biol Soc, 8(10), 6610625.                       

28        Raethjen, J., Muthuraman, M., Kostka, A., Nahrwold, M., Hellriegel, H., Lorenz, D., & Deuschl, G. (2013). Corticomuscular coherence in asymptomatic first-degree relatives of patients with essential tremor. Mov Disord, 28(5), 679-682.                    

27        Muthuraman, M., Hellriegel, H., Paschen, S., Hofschulte, F., Reese, R., Volkmann, J., Witt, K., Deuschl, G., & Raethjen, J. (2013). The central oscillatory network of orthostatic tremor. Mov Disord, 28(10), 1424-1430.                       

26        Muthuraman, M., Hellriegel, H., Groppa, S., Deuschl, G., & Raethjen, J. (2013). The cortical and sub-cortical network of sensory evoked response in healthy subjects. Annu Int Conf IEEE Eng Med Biol Soc, 72(10), 6610762.                  

25        Muthuraman, M., Galka, A., Hong, V. N., Heute, U., Deuschl, G., & Raethjen, J. (2013). Cortico-muscular coherence on artifact corrected EEG-EMG data recorded with a MRI scanner. Annu Int Conf IEEE Eng Med Biol Soc, 4(10), 6610624.                   

24        Muthalib, M., Anwar, A. R., Perrey, S., Dat, M., Galka, A., Wolff, S., Heute, U., Deuschl, G., Raethjen, J., & Muthuraman, M. (2013). Multimodal integration of fNIRS, fMRI and EEG neuroimaging. Clin Neurophysiol., 124(10), 2060-2062.             

23        Moeller, F., Muthuraman, M., Stephani, U., Deuschl, G., Raethjen, J., & Siniatchkin, M. (2013). Representation and propagation of epileptic activity in absences and generalized photoparoxysmal responses. Hum Brain Mapp, 34(8), 1896-1909.              

22        Mideksa, K. G., Hellriegel, H., Hoogenboom, N., Krause, H., Schnitzler, A., Deuschl, G., Raethjen, J., Heute, U., & Muthuraman, M. (2013). Dipole source analysis for readiness potential and field using simultaneously measured EEG and MEG signals. Annu Int Conf IEEE Eng Med Biol Soc, 5(10), 6609762.                     

21        Michels, L., Muthuraman, M., Lüchinger, R., Martin, E., Anwar, A. R., Raethjen, J., Brandeis, D., & Siniatchkin, M. (2013). Developmental changes of functional and directed resting-state connectivities associated with neuronal oscillations in EEG. Neuroimage, 81, 231-242.                      

20        Japaridze, N., Muthuraman, M., Moeller, F., Boor, R., Anwar, A. R., Deuschl, G., Stephani, U., Raethjen, J., & Siniatchkin, M. (2013). Neuronal networks in west syndrome as revealed by source analysis and renormalized partial directed coherence. Brain Topogr, 26(1), 157-170.                     

19        Hossen, A., Muthuraman, M., Al-Hakim, Z., Raethjen, J., Deuschl, G., & Heute, U. (2013). Discrimination of Parkinsonian tremor from essential tremor using statistical signal characterization of the spectrum of accelerometer signal. Biomed Mater Eng, 23(6), 513-531.            

18        Groppa, S., Muthuraman, M., Otto, B., Deuschl, G., Siebner, H. R., & Raethjen, J. (2013). Subcortical substrates of TMS induced modulation of the cortico-cortical connectivity. Brain Stimul, 6(2), 138-146.                 

17        Elshoff, L., Muthuraman, M., Anwar, A. R., Deuschl, G., Stephani, U., Raethjen, J., & Siniatchkin, M. (2013). Dynamic imaging of coherent sources reveals different network connectivity underlying the generation and perpetuation of epileptic seizures. PLoS One, 8(10).                 

16        Anwar, A. R., Muthalib, M., Perrey, S., Galka, A., Granert, O., Wolff, S., Deuschl, G., Raethjen, J., Heute, U., & Muthuraman, M. (2013). Comparison of causality analysis on simultaneously measured fMRI and NIRS signals during motor tasks. Annu Int Conf IEEE Eng Med Biol Soc, 31(10), 6610079.                   

15        Raethjen, J., & Muthuraman, M. (2012). Corticomuscular coupling in human locomotion: muscle drive or gait control? J Physiol, 590(16), 3631-3632.                

14        Muthuraman, M., Tamás, G., Hellriegel, H., Deuschl, G., & Raethjen, J. (2012). Source analysis of beta-synchronisation and cortico-muscular coherence after movement termination based on high resolution electroencephalography. PLoS One, 7(3), 21.            

13        Muthuraman, M., Paschen, S., Hellriegel, H., Groppa, S., Deuschl, G., & Raethjen, J. (2012). Locating the STN-DBS electrodes and resolving their subsequent networks using coherent source analysis on EEG. Annu Int Conf IEEE Eng Med Biol Soc, 3(10), 6346836.                    

12        Muthuraman, M., Heute, U., Arning, K., Anwar, A. R., Elble, R., Deuschl, G., & Raethjen, J. (2012). Oscillating central motor networks in pathological tremors and voluntary movements. What makes the difference? Neuroimage, 60(2), 1331-1339.              

11        Muthuraman, M., Arning, K., Govindan, R. B., Heute, U., Deuschl, G., & Raethjen, J. (2012). Cortical representation of different motor rhythms during bimanual movements. Exp Brain Res, 223(4), 489-504.                 

10        Mideksa, K. G., Hellriegel, H., Hoogenboom, N., Krause, H., Schnitzler, A., Deuschl, G., Raethjen, J., Heute, U., & Muthuraman, M. (2012). Source analysis of median nerve stimulated somatosensory evoked potentials and fields using simultaneously measured EEG and MEG signals. Annu Int Conf IEEE Eng Med Biol Soc,            6(1       0), 6347093.

9          Anwar, A. R., Muthalib, M., Perrey, S., Galka, A., Granert, O., Wolff, S., Deuschl, G., Raethjen, J., Heute, U., & Muthuraman, M. (2012). Directionality analysis on functional magnetic resonance imaging during motor task using Granger causality. Annu Int Conf IEEE Eng Med Biol Soc, 90(10), 6346419.                   

8          Tamás, G., Raethjen, J., Muthuraman, M., Folhoffer, A., Deuschl, G., Szalay, F., Takáts, A., & Kamondi, A. (2011). Disturbed post-movement beta synchronization in Wilson’s disease with neurological manifestation. Neurosci Lett, 494(3), 240-244.                     

7          Muthuraman, M., Hossen, A., Heute, U., Deuschl, G., & Raethjen, J. (2011). A new diagnostic test to distinguish tremulous Parkinson’s disease from advanced essential tremor. Mov Disord, 26(8), 1548-1552.               

6          Muthuraman, M., Heute, U., Deuschl, G., & Raethjen, J. (2010). The central oscillatory network of essential tremor. [Research Support, Non-U S Gov’t]. Annu Int Conf IEEE Eng Med Biol Soc, 5627211.             

5          Fasano, A., Herzog, J., Raethjen, J., Rose, F. E., Muthuraman, M., Volkmann, J., Falk, D., Elble, R., & Deuschl, G. (2010). Gait ataxia in essential tremor is differentially modulated by thalamic stimulation. Brain, 133(Pt 12), 3635-3648.           

4          Raethjen, J., Govindan, R. B., Muthuraman, M., Kopper, F., Volkmann, J., & Deuschl, G. (2009). Cortical correlates of the basic and first harmonic frequency of Parkinsonian tremor. Clin Neurophysiol, 120(10), 1866-1872.                  

3          Muthuraman, M., Raethjen, J., Hellriegel, H., Deuschl, G., & Heute, U. (2008). Imaging coherent sources of tremor related EEG activity in patients with Parkinson’s disease. Annu Int Conf IEEE Eng Med Biol Soc, 9(10), 4650266.             

2          Muthuraman, M., Govindan, R. B., Deuschl, G., Heute, U., & Raethjen, J. (2008). Differentiating phase shift and delay in narrow band coherent signals. Clin Neurophysiol, 119(5), 1062-1070.                 

1          Raethjen, J., Govindan, R. B., Kopper, F., Muthuraman, M., & Deuschl, G. (2007). Cortical involvement in the generation of essential tremor. J Neurophysiol, 97(5), 3219-3228.